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Inositol hexakisphosphate kinase 1 (InsP6K1) regulates neutrophil function in innate immunity by inhibiting PtdIns(3,4,5)P3 signaling

Inositol phosphates (InsP) are widely produced throughout animal and plant tissues. Diphosphoinositol pentakisphosphate (InsP7) contains an energetic pyrophosphate bond. Here, we demonstrate that disruption of InsP6K1, one of the three mammalian InsP6Ks that convert InsP6 to InsP7, confers enhanced...

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Detalles Bibliográficos
Autores principales:	Prasad, Amit, Jia, Yonghui, Chakraborty, Anutosh, Li, Yitang, Jain, Supriya K., Zhong, Jia, Roy, Saurabh Ghosh, Loison, Fabien, Mondal, Subhanjan, Sakai, Jiro, Blanchard, Catlyn, Snyder, Solomon H., Luo, Hongbo R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140608/ https://www.ncbi.nlm.nih.gov/pubmed/21685907 http://dx.doi.org/10.1038/ni.2052

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