YADA: a tool for taking the most out of high-resolution spectra

Summary: YADA can deisotope and decharge high-resolution mass spectra from large peptide molecules, link the precursor monoisotopic peak information to the corresponding tandem mass spectrum, and account for different co-fragmenting ion species (multiplexed spectra). We describe how YADA enables a p...

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Detalles Bibliográficos
Autores principales: Carvalho, Paulo C., Xu, Tao, Han, Xuemei, Cociorva, Daniel, Barbosa, Valmir C., Yates, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140806/
https://www.ncbi.nlm.nih.gov/pubmed/19684088
http://dx.doi.org/10.1093/bioinformatics/btp489
Descripción
Sumario:Summary: YADA can deisotope and decharge high-resolution mass spectra from large peptide molecules, link the precursor monoisotopic peak information to the corresponding tandem mass spectrum, and account for different co-fragmenting ion species (multiplexed spectra). We describe how YADA enables a pipeline consisting of ProLuCID and DTASelect for analyzing large-scale middle-down proteomics data. Availability: http://fields.scripps.edu/yada Contact: paulo@pcarvalho.com Supplementary information: Supplementary data are available at Bioinformatics online.

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