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Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration

BACKGROUND: To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS: Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected fo...

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Autores principales: Turgut, Burak, Uyar, Fatma, Ilhan, Fulya, Demir, Tamer, Celiker, Ulku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140884/
https://www.ncbi.nlm.nih.gov/pubmed/21811525
http://dx.doi.org/10.4021/jocmr2010.03.282w
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author Turgut, Burak
Uyar, Fatma
Ilhan, Fulya
Demir, Tamer
Celiker, Ulku
author_facet Turgut, Burak
Uyar, Fatma
Ilhan, Fulya
Demir, Tamer
Celiker, Ulku
author_sort Turgut, Burak
collection PubMed
description BACKGROUND: To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS: Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected for analysis of IgM and IgG antibody seropositivity for CP and MP by enzyme-linked immunosorbent assay (ELISA). Comparison of the distribution of seropositivity of these antibodies among patients with wet and dry AMD, and controls was performed. A prospective comparative clinical trial was applied. RESULTS: There was no major difference in the distribution of IgM and IgG seropositivity to CP and MP in patients with wet and dry AMD, and in controls (p > 0.05). CONCLUSIONS: We found no significant association between MP as well as CP antibody titers and AMD. It seems that MP or CP infection is not a risk factor for AMD. KEYWORDS: Mycoplasma pneumoniae; Chlamydia pneumoniae; Age-related macular degeneration; Serology
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spelling pubmed-31408842011-08-02 Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration Turgut, Burak Uyar, Fatma Ilhan, Fulya Demir, Tamer Celiker, Ulku J Clin Med Res Original Article BACKGROUND: To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS: Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected for analysis of IgM and IgG antibody seropositivity for CP and MP by enzyme-linked immunosorbent assay (ELISA). Comparison of the distribution of seropositivity of these antibodies among patients with wet and dry AMD, and controls was performed. A prospective comparative clinical trial was applied. RESULTS: There was no major difference in the distribution of IgM and IgG seropositivity to CP and MP in patients with wet and dry AMD, and in controls (p > 0.05). CONCLUSIONS: We found no significant association between MP as well as CP antibody titers and AMD. It seems that MP or CP infection is not a risk factor for AMD. KEYWORDS: Mycoplasma pneumoniae; Chlamydia pneumoniae; Age-related macular degeneration; Serology Elmer Press 2010-04 2010-03-31 /pmc/articles/PMC3140884/ /pubmed/21811525 http://dx.doi.org/10.4021/jocmr2010.03.282w Text en Copyright © 2010, Turgut et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Turgut, Burak
Uyar, Fatma
Ilhan, Fulya
Demir, Tamer
Celiker, Ulku
Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
title Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
title_full Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
title_fullStr Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
title_full_unstemmed Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
title_short Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
title_sort mycoplasma pneumoniae and chlamydia pneumoniae seropositivity in patients with age-related macular degeneration
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140884/
https://www.ncbi.nlm.nih.gov/pubmed/21811525
http://dx.doi.org/10.4021/jocmr2010.03.282w
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