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Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration
BACKGROUND: To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS: Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected fo...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elmer Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140884/ https://www.ncbi.nlm.nih.gov/pubmed/21811525 http://dx.doi.org/10.4021/jocmr2010.03.282w |
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author | Turgut, Burak Uyar, Fatma Ilhan, Fulya Demir, Tamer Celiker, Ulku |
author_facet | Turgut, Burak Uyar, Fatma Ilhan, Fulya Demir, Tamer Celiker, Ulku |
author_sort | Turgut, Burak |
collection | PubMed |
description | BACKGROUND: To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS: Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected for analysis of IgM and IgG antibody seropositivity for CP and MP by enzyme-linked immunosorbent assay (ELISA). Comparison of the distribution of seropositivity of these antibodies among patients with wet and dry AMD, and controls was performed. A prospective comparative clinical trial was applied. RESULTS: There was no major difference in the distribution of IgM and IgG seropositivity to CP and MP in patients with wet and dry AMD, and in controls (p > 0.05). CONCLUSIONS: We found no significant association between MP as well as CP antibody titers and AMD. It seems that MP or CP infection is not a risk factor for AMD. KEYWORDS: Mycoplasma pneumoniae; Chlamydia pneumoniae; Age-related macular degeneration; Serology |
format | Online Article Text |
id | pubmed-3140884 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Elmer Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-31408842011-08-02 Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration Turgut, Burak Uyar, Fatma Ilhan, Fulya Demir, Tamer Celiker, Ulku J Clin Med Res Original Article BACKGROUND: To determine a possible relation between Mycoplasma pneumoniae (MP) or Chlamidia pneumoniae (CP) seropositivity and age-related macular degeneration (AMD). METHODS: Sixty patients (20 wet AMD, 20 dry AMD and 20 non-AMD controls) were included in the study. Serum samples were collected for analysis of IgM and IgG antibody seropositivity for CP and MP by enzyme-linked immunosorbent assay (ELISA). Comparison of the distribution of seropositivity of these antibodies among patients with wet and dry AMD, and controls was performed. A prospective comparative clinical trial was applied. RESULTS: There was no major difference in the distribution of IgM and IgG seropositivity to CP and MP in patients with wet and dry AMD, and in controls (p > 0.05). CONCLUSIONS: We found no significant association between MP as well as CP antibody titers and AMD. It seems that MP or CP infection is not a risk factor for AMD. KEYWORDS: Mycoplasma pneumoniae; Chlamydia pneumoniae; Age-related macular degeneration; Serology Elmer Press 2010-04 2010-03-31 /pmc/articles/PMC3140884/ /pubmed/21811525 http://dx.doi.org/10.4021/jocmr2010.03.282w Text en Copyright © 2010, Turgut et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Turgut, Burak Uyar, Fatma Ilhan, Fulya Demir, Tamer Celiker, Ulku Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration |
title | Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration |
title_full | Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration |
title_fullStr | Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration |
title_full_unstemmed | Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration |
title_short | Mycoplasma Pneumoniae and Chlamydia Pneumoniae Seropositivity in Patients With Age-Related Macular Degeneration |
title_sort | mycoplasma pneumoniae and chlamydia pneumoniae seropositivity in patients with age-related macular degeneration |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140884/ https://www.ncbi.nlm.nih.gov/pubmed/21811525 http://dx.doi.org/10.4021/jocmr2010.03.282w |
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