A Rare Tumour of the Breast: Carcinosarcoma

Carcinosarcoma of the breast, also known as metaplastic carcinoma, is rare with very few cases reported in the literature. A 46-year old female patient presented with a mass in her left breast. Physical examination, ultrasonography and mammography findings were consistent with malignancy. The mass w...

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Autores principales: Ilhan, Enver, Vardar, Enver, Ozkok, Guliz, Sezgin, Arsenal, Sahin, Safak, Teker, Kenan, Postaci, Hakan, Yildirim, Mehmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elmer Press 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140887/
https://www.ncbi.nlm.nih.gov/pubmed/21811528
http://dx.doi.org/10.4021/jocmr2010.03.275w
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author Ilhan, Enver
Vardar, Enver
Ozkok, Guliz
Sezgin, Arsenal
Sahin, Safak
Teker, Kenan
Postaci, Hakan
Yildirim, Mehmet
author_facet Ilhan, Enver
Vardar, Enver
Ozkok, Guliz
Sezgin, Arsenal
Sahin, Safak
Teker, Kenan
Postaci, Hakan
Yildirim, Mehmet
author_sort Ilhan, Enver
collection PubMed
description Carcinosarcoma of the breast, also known as metaplastic carcinoma, is rare with very few cases reported in the literature. A 46-year old female patient presented with a mass in her left breast. Physical examination, ultrasonography and mammography findings were consistent with malignancy. The mass was totally removed. Histopathological examination revealed carcinosarcoma of the breast. Histologic grade of the tumour was III. Ki67 proliferation index was found 40% positive. Tumour cells were positive for p53 (70% positive), c-erb-B2 (5% positive), pancytokeratin and EMA in carcinomatous areas, and vimentin in sarcomatous areas. There was no metastasis in axillary lymph node and distant metastasis. The patient is receiving chemotherapy and is under follow-up in the 54th month. Along with a review of the literature, we present the information regarding the clinical and histological findings and treatment of the patient who was operated due to breast carcinosarcoma. KEYWORDS: Breast; Carcinoma; Carcinosarcoma
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spelling pubmed-31408872011-08-02 A Rare Tumour of the Breast: Carcinosarcoma Ilhan, Enver Vardar, Enver Ozkok, Guliz Sezgin, Arsenal Sahin, Safak Teker, Kenan Postaci, Hakan Yildirim, Mehmet J Clin Med Res Case Report Carcinosarcoma of the breast, also known as metaplastic carcinoma, is rare with very few cases reported in the literature. A 46-year old female patient presented with a mass in her left breast. Physical examination, ultrasonography and mammography findings were consistent with malignancy. The mass was totally removed. Histopathological examination revealed carcinosarcoma of the breast. Histologic grade of the tumour was III. Ki67 proliferation index was found 40% positive. Tumour cells were positive for p53 (70% positive), c-erb-B2 (5% positive), pancytokeratin and EMA in carcinomatous areas, and vimentin in sarcomatous areas. There was no metastasis in axillary lymph node and distant metastasis. The patient is receiving chemotherapy and is under follow-up in the 54th month. Along with a review of the literature, we present the information regarding the clinical and histological findings and treatment of the patient who was operated due to breast carcinosarcoma. KEYWORDS: Breast; Carcinoma; Carcinosarcoma Elmer Press 2010-04 2010-03-25 /pmc/articles/PMC3140887/ /pubmed/21811528 http://dx.doi.org/10.4021/jocmr2010.03.275w Text en Copyright © 2010, Ilhan et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ilhan, Enver
Vardar, Enver
Ozkok, Guliz
Sezgin, Arsenal
Sahin, Safak
Teker, Kenan
Postaci, Hakan
Yildirim, Mehmet
A Rare Tumour of the Breast: Carcinosarcoma
title A Rare Tumour of the Breast: Carcinosarcoma
title_full A Rare Tumour of the Breast: Carcinosarcoma
title_fullStr A Rare Tumour of the Breast: Carcinosarcoma
title_full_unstemmed A Rare Tumour of the Breast: Carcinosarcoma
title_short A Rare Tumour of the Breast: Carcinosarcoma
title_sort rare tumour of the breast: carcinosarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140887/
https://www.ncbi.nlm.nih.gov/pubmed/21811528
http://dx.doi.org/10.4021/jocmr2010.03.275w
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