Cargando…

Evidence for a Prepore Stage in the Action of Clostridium perfringens Epsilon Toxin

Clostridium perfringens epsilon toxin (ETX) rapidly kills MDCK II cells at 37°C, but not 4°C. The current study shows that, in MDCK II cells, ETX binds and forms an oligomeric complex equally well at 37°C and 4°C but only forms a pore at 37°C. However, the complex formed in MDCK cells treated with E...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robertson, Susan L., Li, Jihong, Uzal, Francisco A., McClane, Bruce A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140917/ https://www.ncbi.nlm.nih.gov/pubmed/21814565 http://dx.doi.org/10.1371/journal.pone.0022053

Ejemplares similares

Proteolytic Processing and Activation of Clostridium perfringens Epsilon Toxin by Caprine Small Intestinal Contents
por: Freedman, John C., et al.
Publicado: (2014)

Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins
por: Navarro, Mauricio A., et al.
Publicado: (2018)

Clostridium perfringens Epsilon Toxin Increases the Small Intestinal Permeability in Mice and Rats
por: Goldstein, Jorge, et al.
Publicado: (2009)

Correction: Clostridium perfringens Epsilon Toxin Increases the Small Intestinal Permeability in Mice and Rats
por: Goldstein, Jorge, et al.
Publicado: (2013)

Sialidases Affect the Host Cell Adherence and Epsilon Toxin-Induced Cytotoxicity of Clostridium perfringens Type D Strain CN3718
por: Li, Jihong, et al.
Publicado: (2011)

Clostridium perfringens Sialidases: Potential Contributors to Intestinal Pathogenesis and Therapeutic Targets
por: Li, Jihong, et al.
Publicado: (2016)

Effects of Claudin-1 on the Action of Clostridium perfringens Enterotoxin in Caco-2 Cells
por: Mehdizadeh Gohari, Iman, et al.
Publicado: (2019)

NanI Sialidase Enhances the Action of Clostridium perfringens Enterotoxin in the Presence of Mucus
por: Navarro, Mauricio A., et al.
Publicado: (2021)

Pathogenicity and virulence of Clostridium perfringens
por: Mehdizadeh Gohari, Iman, et al.
Publicado: (2021)

Clostridium Perfringens Toxins Involved in Mammalian Veterinary Diseases
por: Uzal, F. A., et al.
Publicado: (2010)

Enterotoxigenic Clostridium perfringens: Detection and Identification
por: Miyamoto, Kazuaki, et al.
Publicado: (2012)

Reevaluation of whether a Functional Agr-like Quorum-Sensing System Is Necessary for Production of Wild-Type Levels of Epsilon-Toxin by Clostridium perfringens Type D Strains
por: Mehdizadeh Gohari, Iman, et al.
Publicado: (2022)

Evidence That VirS Is a Receptor for the Signaling Peptide of the Clostridium perfringens Agr-like Quorum Sensing System
por: Li, Jihong, et al.
Publicado: (2020)

Pathology and Pathogenesis of Brain Lesions Produced by Clostridium perfringens Type D Epsilon Toxin
por: Finnie, John W., et al.
Publicado: (2022)

Clostridium perfringens Enterotoxin: Action, Genetics, and Translational Applications
por: Freedman, John C., et al.
Publicado: (2016)

NanH Is Produced by Sporulating Cultures of Clostridium perfringens Type F Food Poisoning Strains and Enhances the Cytotoxicity of C. perfringens Enterotoxin
por: Li, Jihong, et al.
Publicado: (2021)

Epsilon-Toxin Production by Clostridium perfringens Type D Strain CN3718 Is Dependent upon the agr Operon but Not the VirS/VirR Two-Component Regulatory System
por: Chen, Jianming, et al.
Publicado: (2011)

The Agr-Like Quorum-Sensing System Is Important for Clostridium perfringens Type A Strain ATCC 3624 To Cause Gas Gangrene in a Mouse Model
por: Navarro, Mauricio A., et al.
Publicado: (2020)

Correction for Chen et al., Epsilon-Toxin Production by Clostridium perfringens Type D Strain CN3718 Is Dependent upon the agr Operon but Not the VirS/VirR Two-Component Regulatory System
por: Chen, Jianming, et al.
Publicado: (2015)

Retraction for Chen et al., “Epsilon-Toxin Production by Clostridium perfringens Type D Strain CN3718 Is Dependent upon the agr Operon but Not the VirS/VirR Two-Component Regulatory System”
por: Chen, Jianming, et al.
Publicado: (2022)

Characterizing the Contributions of Various Clostridium perfringens Enterotoxin Properties to In Vivo and In Vitro Permeability Effects
por: Shrestha, Archana, et al.
Publicado: (2022)

A Novel Small Acid Soluble Protein Variant Is Important for Spore Resistance of Most Clostridium perfringens Food Poisoning Isolates
por: Li, Jihong, et al.
Publicado: (2008)

Use of an EZ-Tn5-Based Random Mutagenesis System to Identify a Novel Toxin Regulatory Locus in Clostridium perfringens Strain 13
por: Vidal, Jorge E., et al.
Publicado: (2009)

Organization of the cpe Locus in CPE-Positive Clostridium perfringens Type C and D Isolates
por: Li, Jihong, et al.
Publicado: (2010)

Epsilon toxin–producing Clostridium perfringens colonize the multiple sclerosis gut microbiome overcoming CNS immune privilege
por: Ma, Yinghua, et al.
Publicado: (2023)

Evidence of Clostridium perfringens epsilon toxin associated with multiple sclerosis
por: Wagley, Sariqa, et al.
Publicado: (2018)

The VirS/VirR Two-Component System Regulates the Anaerobic Cytotoxicity, Intestinal Pathogenicity, and Enterotoxemic Lethality of Clostridium perfringens Type C Isolate CN3685
por: Ma, Menglin, et al.
Publicado: (2011)

The pore structure of Clostridium perfringens epsilon toxin
por: Savva, Christos G., et al.
Publicado: (2019)

Identification of Novel Clostridium perfringens Type E Strains That Carry an Iota Toxin Plasmid with a Functional Enterotoxin Gene
por: Miyamoto, Kazuaki, et al.
Publicado: (2011)

Identification of orphan histidine kinases that impact sporulation and enterotoxin production by Clostridium perfringens type F strain SM101 in a pathophysiologically-relevant ex vivo mouse intestinal contents model
por: Mehdizadeh Gohari, Iman, et al.
Publicado: (2023)

The Potential Therapeutic Agent Mepacrine Protects Caco-2 Cells against Clostridium perfringens Enterotoxin Action
por: Freedman, John C., et al.
Publicado: (2017)

Is Clostridium perfringens epsilon toxin associated with multiple sclerosis?
por: Titball, Richard W, et al.
Publicado: (2023)

Human Claudin-8 and -14 Are Receptors Capable of Conveying the Cytotoxic Effects of Clostridium perfringens Enterotoxin
por: Shrestha, Archana, et al.
Publicado: (2013)

Genetic Characterization of Type A Enterotoxigenic Clostridium perfringens Strains
por: Deguchi, Agi, et al.
Publicado: (2009)

Further Characterization of Clostridium perfringens Small Acid Soluble Protein-4 (Ssp4) Properties and Expression
por: Li, Jihong, et al.
Publicado: (2009)

CodY Is a Global Regulator of Virulence-Associated Properties for Clostridium perfringens Type D Strain CN3718
por: Li, Jihong, et al.
Publicado: (2013)

Bystander Host Cell Killing Effects of Clostridium perfringens Enterotoxin
por: Shrestha, Archana, et al.
Publicado: (2016)

Identification of an Important Orphan Histidine Kinase for the Initiation of Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strain SM101
por: Freedman, John C., et al.
Publicado: (2019)

Use of Clostridium perfringens Enterotoxin and the Enterotoxin Receptor-Binding Domain (C-CPE) for Cancer Treatment: Opportunities and Challenges
por: Gao, Zhijian, et al.
Publicado: (2012)

Characterization of NanR Regulation of Sialidase Production, Sporulation and Enterotoxin Production by Clostridium perfringens Type F Strains Carrying a Chromosomal Enterotoxin Gene
por: Li, Jihong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0mq7gmj8i2jge4vuaoivv7kc71