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Somatic Genetics Empowers the Mouse for Modeling and Interrogating Developmental and Disease Processes

With recent advances in genomic technologies, candidate human disease genes are being mapped at an accelerated pace. There is a clear need to move forward with genetic tools that can efficiently validate these mutations in vivo. Murine somatic mutagenesis is evolving to fulfill these needs with tool...

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Detalles Bibliográficos
Autores principales: Landrette, Sean F., Xu, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140981/
https://www.ncbi.nlm.nih.gov/pubmed/21814514
http://dx.doi.org/10.1371/journal.pgen.1002110