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A Functional Variant at a Prostate Cancer Predisposition Locus at 8q24 Is Associated with PVT1 Expression
Genetic mapping studies have identified multiple cancer susceptibility regions at chromosome 8q24, upstream of the MYC oncogene. MYC has been widely presumed as the regulated target gene, but definitive evidence functionally linking these cancer regions with MYC has been difficult to obtain. Here we...
Autores principales: | Meyer, Kerstin B., Maia, Ana-Teresa, O'Reilly, Martin, Ghoussaini, Maya, Prathalingam, Radhika, Porter-Gill, Patricia, Ambs, Stefan, Prokunina-Olsson, Ludmila, Carroll, Jason, Ponder, Bruce A. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140991/ https://www.ncbi.nlm.nih.gov/pubmed/21814516 http://dx.doi.org/10.1371/journal.pgen.1002165 |
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