Myeloid IκBα Deficiency Promotes Atherogenesis by Enhancing Leukocyte Recruitment to the Plaques

Activation of the transcription factor NF-κB appears to be involved in different stages of atherogenesis. In this paper we investigate the role of NF-κB inhibitor IκBα in atherosclerosis. Myeloid-specific deletion of IκBα results in larger and more advanced lesions in LDL-R-deficient mice without af...

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Detalles Bibliográficos
Autores principales: Goossens, Pieter, Vergouwe, Monique N., Gijbels, Marion J. J., Curfs, Danielle M. J., van Woezik, Johannes H. G., Hoeksema, Marten A., Xanthoulea, Sofia, Leenen, Pieter J. M., Rupec, Rudolf A., Hofker, Marten H., de Winther, Menno P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141029/
https://www.ncbi.nlm.nih.gov/pubmed/21814576
http://dx.doi.org/10.1371/journal.pone.0022327

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