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A Role for the Chemokine RANTES in Regulating CD8 T Cell Responses during Chronic Viral Infection
RANTES (CCL5) is a chemokine expressed by many hematopoietic and non-hematopoietic cell types that plays an important role in homing and migration of effector and memory T cells during acute infections. The RANTES receptor, CCR5, is a major target of anti-HIV drugs based on blocking viral entry. How...
Autores principales: | Crawford, Alison, Angelosanto, Jill Marie, Nadwodny, Kim Lynn, Blackburn, Shawn D., Wherry, E. John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141034/ https://www.ncbi.nlm.nih.gov/pubmed/21814510 http://dx.doi.org/10.1371/journal.ppat.1002098 |
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