Cargando…

The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans

The type II poly(A)-binding protein PABP2/PABPN1 functions in general mRNA metabolism by promoting poly(A) tail formation in mammals and flies. It also participates in poly(A) tail shortening of specific mRNAs in flies, and snoRNA biogenesis in yeast. We have identified Caenorhabditis elegans pabp-2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hurschler, Benjamin A., Harris, David T., Großhans, Helge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141255/ https://www.ncbi.nlm.nih.gov/pubmed/21415013 http://dx.doi.org/10.1093/nar/gkr145

Ejemplares similares

Nuclear and cytoplasmic poly(A) binding proteins (PABPs) favor distinct transcripts and isoforms
por: Nicholson-Shaw, Angela L, et al.
Publicado: (2022)

Engineering of a conditional allele reveals multiple roles of XRN2 in Caenorhabditis elegans development and substrate specificity in microRNA turnover
por: Miki, Takashi S., et al.
Publicado: (2014)

ALG-5 is a miRNA-associated Argonaute required for proper developmental timing in the Caenorhabditis elegans germline
por: Brown, Kristen C., et al.
Publicado: (2017)

Orthologs of the Caenorhabditis elegans heterochronic genes have divergent functions in Caenorhabditis briggsae
por: Ivanova, Maria, et al.
Publicado: (2023)

Co-regulation of alternative splicing by diverse splicing factors in Caenorhabditis elegans
por: Barberan-Soler, Sergio, et al.
Publicado: (2011)

Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs
por: Burgess, Hannah M., et al.
Publicado: (2011)

LARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA
por: Cruz-Gallardo, Isabel, et al.
Publicado: (2019)

TERRA expression is regulated by the telomere-binding proteins POT-1 and POT-2 in Caenorhabditis elegans
por: Manzato, Caterina, et al.
Publicado: (2023)

A small nucleolar RNA functions in rRNA processing in Caenorhabditis elegans
por: Hokii, Yusuke, et al.
Publicado: (2010)

Poly(A)-binding proteins are required for microRNA-mediated silencing and to promote target deadenylation in C. elegans
por: Flamand, Mathieu N., et al.
Publicado: (2016)

The Caenorhabditis elegans intermediate-size transcriptome shows high degree of stage-specific expression
por: Wang, Yunfei, et al.
Publicado: (2011)

Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3)
por: Li, Kuohan, et al.
Publicado: (2021)

The slicing activity of miRNA-specific Argonautes is essential for the miRNA pathway in C. elegans
por: Bouasker, Samir, et al.
Publicado: (2012)

miR-58 family and TGF-β pathways regulate each other in Caenorhabditis elegans
por: de Lucas, María Pilar, et al.
Publicado: (2015)

Stepwise assembly of multiple Lin28 proteins on the terminal loop of let-7 miRNA precursors
por: Desjardins, Alexandre, et al.
Publicado: (2014)

Solution structure of a let-7 miRNA:lin-41 mRNA complex from C. elegans
por: Cevec, Mirko, et al.
Publicado: (2008)

The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans
por: Clark, Alejandra M., et al.
Publicado: (2010)

The Leishmania PABP1–eIF4E4 interface: a novel 5′–3′ interaction architecture for trans-spliced mRNAs
por: dos Santos Rodrigues, Fabio Henrique, et al.
Publicado: (2019)

The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling
por: Rüegger, Stefan, et al.
Publicado: (2015)

Remodeling of the Caenorhabditis elegans non-coding RNA transcriptome by heat shock
por: Schreiner, William P, et al.
Publicado: (2019)

The ribonuclease DIS3 promotes let-7 miRNA maturation by degrading the pluripotency factor LIN28B mRNA
por: Segalla, Simona, et al.
Publicado: (2015)

DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans
por: Longman, Dasa, et al.
Publicado: (2013)

Alzheimer‐related protein APL‐1 modulates lifespan through heterochronic gene regulation in Caenorhabditis elegans
por: Ewald, Collin Y., et al.
Publicado: (2016)

Depletion of Nuclear Poly(A) Binding Protein PABPN1 Produces a Compensatory Response by Cytoplasmic PABP4 and PABP5 in Cultured Human Cells
por: Bhattacharjee, Rumpa Biswas, et al.
Publicado: (2012)

A branched heterochronic pathway directs juvenile-to-adult transition through two LIN-29 isoforms
por: Azzi, Chiara, et al.
Publicado: (2020)

Poly(A) RNA and Paip2 act as allosteric regulators of poly(A)-binding protein
por: Lee, Seung Hwan, et al.
Publicado: (2014)

Structure of the Caenorhabditis elegans m(6)A methyltransferase METT10 that regulates SAM homeostasis
por: Ju, Jue, et al.
Publicado: (2023)

The Caenorhabditis elegans GW182 protein AIN-1 interacts with PAB-1 and subunits of the PAN2-PAN3 and CCR4-NOT deadenylase complexes
por: Kuzuoğlu-Öztürk, Duygu, et al.
Publicado: (2012)

DB-PABP: a database of polyanion-binding proteins
por: Fang, Jianwen, et al.
Publicado: (2008)

TEG-1 CD2BP2 controls miRNA levels by regulating miRISC stability in C. elegans and human cells
por: Wang, Chris, et al.
Publicado: (2017)

XRN2 Autoregulation and Control of Polycistronic Gene Expresssion in Caenorhabditis elegans
por: Miki, Takashi S., et al.
Publicado: (2016)

RNA-binding protein GLD-1/quaking genetically interacts with the mir-35 and the let-7 miRNA pathways in Caenorhabditis elegans
por: Akay, Alper, et al.
Publicado: (2013)

The double-stranded RNA binding protein RDE-4 can act cell autonomously during feeding RNAi in C. elegans
por: Raman, Pravrutha, et al.
Publicado: (2017)

Alternative Poly(A) Tails Meet miRNA Targeting in Caenorhabditis elegans
por: Khraiwesh, Basel, et al.
Publicado: (2017)

A specific role for the C-terminal region of the Poly(A)-binding protein in mRNA decay
por: Simón, Ernesto, et al.
Publicado: (2007)

Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition
por: Wydro, Mateusz, et al.
Publicado: (2010)

The Lin28 cold-shock domain remodels pre-let-7 microRNA
por: Mayr, Florian, et al.
Publicado: (2012)

Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA
por: Zoltner, Martin, et al.
Publicado: (2018)

Functional characterization of C. elegans Y-box-binding proteins reveals tissue-specific functions and a critical role in the formation of polysomes
por: Arnold, Andreas, et al.
Publicado: (2014)

Poly(A) binding protein, C-terminally truncated by the hepatitis A virus proteinase 3C, inhibits viral translation
por: Zhang, Bo, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_37p7ul6pc34c9ejsaillceljak