Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes

Histone modification regulates gene expression, and one major regulatory step in this process is the ability of proteins that recognize epigenetic marks to recruit enzymes required to specify transcriptional outcome. Here we show that BRD7 is a component of hSWI–SNF complexes that interacts with PRM...

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Detalles Bibliográficos
Autores principales: Tae, Sookil, Karkhanis, Vrajesh, Velasco, Kevin, Yaneva, Mariana, Erdjument-Bromage, Hediye, Tempst, Paul, Sif, Saïd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141267/
https://www.ncbi.nlm.nih.gov/pubmed/21447565
http://dx.doi.org/10.1093/nar/gkr170

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