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Principal component analysis-based filtering improves detection for Affymetrix gene expression arrays
Gene expression array technology has reached the stage of being routinely used to study clinical samples in search of diagnostic and prognostic biomarkers. Due to the nature of array experiments, which examine the expression of tens of thousands of genes simultaneously, the number of null hypotheses...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141272/ https://www.ncbi.nlm.nih.gov/pubmed/21525126 http://dx.doi.org/10.1093/nar/gkr241 |