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Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil

In world Helminthes infections are the most widespread of all the infections in humans. The morbidity due to parasitic diseases has been increasing in our population. The gastrointestinal helminthes become resistant to the currently available anthelmintic drugs. Anthelmintic substances having consid...

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Detalles Bibliográficos
Autores principales: Taur, D. J., Kulkarni, V. B., Patil, R. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications Pvt Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141301/
https://www.ncbi.nlm.nih.gov/pubmed/21808553
http://dx.doi.org/10.4103/0974-8490.65504
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author Taur, D. J.
Kulkarni, V. B.
Patil, R. Y.
author_facet Taur, D. J.
Kulkarni, V. B.
Patil, R. Y.
author_sort Taur, D. J.
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description In world Helminthes infections are the most widespread of all the infections in humans. The morbidity due to parasitic diseases has been increasing in our population. The gastrointestinal helminthes become resistant to the currently available anthelmintic drugs. Anthelmintic substances having considerable toxicity to human beings are present in foods derived from livestock, posing a serious threat to human health. Due to this, there is a need to derive new chemical substances from natural sources, for helminthes control. In this study, volatile oil isolated from Eucalyptus globulus Labill was evaluated for its anthelmintic activity on adult Indian earthworms, Pheretima posthuma, which have anatomical and physiological resemblance with the intestinal roundworm parasites of human beings. In concentrations of 0.05, 0.01 and 0.15 ml/ml, respectively, all the oil samples showed potent anthelmintic activity as compared to that of the standard drug albendazole at a concentration of 10 mg/ml.
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spelling pubmed-31413012011-08-01 Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil Taur, D. J. Kulkarni, V. B. Patil, R. Y. Pharmacognosy Res Original Article In world Helminthes infections are the most widespread of all the infections in humans. The morbidity due to parasitic diseases has been increasing in our population. The gastrointestinal helminthes become resistant to the currently available anthelmintic drugs. Anthelmintic substances having considerable toxicity to human beings are present in foods derived from livestock, posing a serious threat to human health. Due to this, there is a need to derive new chemical substances from natural sources, for helminthes control. In this study, volatile oil isolated from Eucalyptus globulus Labill was evaluated for its anthelmintic activity on adult Indian earthworms, Pheretima posthuma, which have anatomical and physiological resemblance with the intestinal roundworm parasites of human beings. In concentrations of 0.05, 0.01 and 0.15 ml/ml, respectively, all the oil samples showed potent anthelmintic activity as compared to that of the standard drug albendazole at a concentration of 10 mg/ml. Medknow Publications Pvt Ltd 2010 /pmc/articles/PMC3141301/ /pubmed/21808553 http://dx.doi.org/10.4103/0974-8490.65504 Text en Copyright: © Pharmacognosy Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Taur, D. J.
Kulkarni, V. B.
Patil, R. Y.
Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
title Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
title_full Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
title_fullStr Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
title_full_unstemmed Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
title_short Chromatographic evaluation and anthelmintic activity of Eucalyptus globulus oil
title_sort chromatographic evaluation and anthelmintic activity of eucalyptus globulus oil
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141301/
https://www.ncbi.nlm.nih.gov/pubmed/21808553
http://dx.doi.org/10.4103/0974-8490.65504
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