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Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation

An unregulated neuroinflammation accompanies numerous chronic and acute neurodegenerative disorders and it is postulated that such a neuroinflammatory component likely exacerbates disease progression. A key player in brain inflammation is the microglial cell; a vital soluble factor synthesized by ac...

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Detalles Bibliográficos
Autores principales: Tweedie, David, Frankola, Kathryn A., Luo, Weiming, Li, Yazhou, Greig, Nigel H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141331/
https://www.ncbi.nlm.nih.gov/pubmed/21792375
http://dx.doi.org/10.2174/1874091X01105010037