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Does prolonged β-lactam infusions improve clinical outcomes compared to intermittent infusions? A meta-analysis and systematic review of randomized, controlled trials

BACKGROUND: The emergence of multi-drug resistant Gram-negatives (MDRGNs) coupled with an alarming scarcity of new antibiotics has forced the optimization of the therapeutic potential of available antibiotics. To exploit the time above the minimum inhibitory concentration mechanism of β-lactams, pro...

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Detalles Bibliográficos
Autores principales:	Tamma, Pranita D, Putcha, Nirupama, Suh, Yong D, Van Arendonk, Kyle J, Rinke, Michael L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141415/ https://www.ncbi.nlm.nih.gov/pubmed/21696619 http://dx.doi.org/10.1186/1471-2334-11-181

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