Physiologic and molecular consequences of endothelial Bmpr2 mutation

BACKGROUND: Pulmonary arterial hypertension (PAH) is thought to be driven by dysfunction of pulmonary vascular microendothelial cells (PMVEC). Most hereditary PAH is associated with BMPR2 mutations. However, the physiologic and molecular consequences of expression of BMPR2 mutations in PMVEC are unk...

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Detalles Bibliográficos
Autores principales: Majka, Susan, Hagen, Moira, Blackwell, Thomas, Harral, Julie, Johnson, Jennifer A, Gendron, Robert, Paradis, Helene, Crona, Daniel, Loyd, James E, Nozik-Grayck, Eva, Stenmark, Kurt R, West, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141420/
https://www.ncbi.nlm.nih.gov/pubmed/21696628
http://dx.doi.org/10.1186/1465-9921-12-84

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