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Molecular and cellular correlates of the CIITA-mediated inhibition of HTLV-2 Tax-2 transactivator function resulting in loss of viral replication

BACKGROUND: MHC class II transactivator CIITA inhibits the function of HTLV-2 Tax-2 viral transactivator and, consequently, the replication of the virus in infected cells. Moreover overexpression of the nuclear factor NF-YB, that cooperates with CIITA for the expression of MHC class II genes, result...

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Detalles Bibliográficos
Autores principales:	Orlandi, Chiara, Forlani, Greta, Tosi, Giovanna, Accolla, Roberto S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141499/ https://www.ncbi.nlm.nih.gov/pubmed/21736733 http://dx.doi.org/10.1186/1479-5876-9-106

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