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High prevalence of potential biases threatens the interpretation of trials in patients with chronic disease
BACKGROUND: The complexity of chronic diseases is a challenge for investigators conducting randomized trials. The causes for this include the often difficult control for confounding, the selection of outcomes from many potentially important outcomes, the risk of missing data with long follow-up and...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141538/ https://www.ncbi.nlm.nih.gov/pubmed/21663701 http://dx.doi.org/10.1186/1741-7015-9-73 |