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Blocking premature reverse transcription fails to rescue the HIV-1 nucleocapsid-mutant replication defect

BACKGROUND: The nucleocapsid (NC) protein of HIV-1 is critical for viral replication. Mutational analyses have demonstrated its involvement in viral assembly, genome packaging, budding, maturation, reverse transcription, and integration. We previously reported that two conservative NC mutations, His...

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Detalles Bibliográficos
Autores principales:	Thomas, James A, Shatzer, Teresa L, Gorelick, Robert J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141651/ https://www.ncbi.nlm.nih.gov/pubmed/21682883 http://dx.doi.org/10.1186/1742-4690-8-46

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