Copy number loss of (src homology 2 domain containing)-transforming protein 2 (SHC2) gene: discordant loss in monozygotic twins and frequent loss in patients with multiple system atrophy

BACKGROUND: Multiple system atrophy (MSA) is a sporadic disease. Its pathogenesis may involve multiple genetic and nongenetic factors, but its etiology remains largely unknown. We hypothesized that the genome of a patient with MSA would demonstrate copy number variations (CNVs) in the genes or genom...

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Detalles Bibliográficos
Autores principales: Sasaki, Hidenao, Emi, Mitsuru, Iijima, Hiroshi, Ito, Noriko, Sato, Hidenori, Yabe, Ichiro, Kato, Takeo, Utsumi, Jun, Matsubara, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141657/
https://www.ncbi.nlm.nih.gov/pubmed/21658278
http://dx.doi.org/10.1186/1756-6606-4-24

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