Cargando…

Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report

INTRODUCTION: Giant condyloma acuminatum, also called a Buschke-Löwenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surp...

Descripción completa

Detalles Bibliográficos
Autores principales: Nthumba, Peter M, Ngure, Peter, Nyoro, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141715/
https://www.ncbi.nlm.nih.gov/pubmed/21722389
http://dx.doi.org/10.1186/1752-1947-5-272
_version_ 1782208742420381696
author Nthumba, Peter M
Ngure, Peter
Nyoro, Patrick
author_facet Nthumba, Peter M
Ngure, Peter
Nyoro, Patrick
author_sort Nthumba, Peter M
collection PubMed
description INTRODUCTION: Giant condyloma acuminatum, also called a Buschke-Löwenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surprisingly even rarer. CASE PRESENTATION: In this report, we present the case of a 42-year-old African man with AIDS who was undergoing anti-retroviral therapy. He was found to have a giant condyloma acuminatum of the scrotum. Wide surgical excision and scrotal reconstruction with a pedicled anterolateral thigh flap was performed, significantly improving his quality of life. CONCLUSION: Decision making regarding the goals of surgical intervention in the terminally ill is a complex process. The options include conservative medical palliation or palliative excision versus a curative excision that has the potential for significant morbidity. Wide surgical excision with local flap reconstruction significantly improved the quality of life of the patient described herein. The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients.
format Online
Article
Text
id pubmed-3141715
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-31417152011-07-23 Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report Nthumba, Peter M Ngure, Peter Nyoro, Patrick J Med Case Reports Case Report INTRODUCTION: Giant condyloma acuminatum, also called a Buschke-Löwenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surprisingly even rarer. CASE PRESENTATION: In this report, we present the case of a 42-year-old African man with AIDS who was undergoing anti-retroviral therapy. He was found to have a giant condyloma acuminatum of the scrotum. Wide surgical excision and scrotal reconstruction with a pedicled anterolateral thigh flap was performed, significantly improving his quality of life. CONCLUSION: Decision making regarding the goals of surgical intervention in the terminally ill is a complex process. The options include conservative medical palliation or palliative excision versus a curative excision that has the potential for significant morbidity. Wide surgical excision with local flap reconstruction significantly improved the quality of life of the patient described herein. The challenges presented by emerging or unusual presentations of surgical pathology secondary to HIV and AIDS in patients who are on anti-retroviral therapy provide an opportunity for research and the establishment of guidelines for the use of adjuvant chemotherapy in these patients. BioMed Central 2011-07-02 /pmc/articles/PMC3141715/ /pubmed/21722389 http://dx.doi.org/10.1186/1752-1947-5-272 Text en Copyright ©2011 Nthumba et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nthumba, Peter M
Ngure, Peter
Nyoro, Patrick
Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
title Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
title_full Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
title_fullStr Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
title_full_unstemmed Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
title_short Giant condyloma acuminatum of the scrotum in a man with AIDS: a case report
title_sort giant condyloma acuminatum of the scrotum in a man with aids: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141715/
https://www.ncbi.nlm.nih.gov/pubmed/21722389
http://dx.doi.org/10.1186/1752-1947-5-272
work_keys_str_mv AT nthumbapeterm giantcondylomaacuminatumofthescrotuminamanwithaidsacasereport
AT ngurepeter giantcondylomaacuminatumofthescrotuminamanwithaidsacasereport
AT nyoropatrick giantcondylomaacuminatumofthescrotuminamanwithaidsacasereport