Isolation of mouse mesenchymal stem cells with normal ploidy from bone marrows by reducing oxidative stress in combination with extracellular matrix

BACKGROUND: Isolation of mouse MSCs (mMSCs) with normal ploidy from bone marrow remains challenging. mMSCs isolated under 20% O(2 )are frequently contaminated by overgrown hematopoietic cells, and could also be especially vulnerable to oxidative damage, resulting in chromosomal instability. Culture...

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Detalles Bibliográficos
Autores principales: Fan, Guokuan, Wen, Lai, Li, Minshu, Li, Chao, Luo, Benping, Wang, Fang, Zhou, Lingjun, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141734/
https://www.ncbi.nlm.nih.gov/pubmed/21729331
http://dx.doi.org/10.1186/1471-2121-12-30

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