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Gβγ subunits inhibit Epac-induced melanoma cell migration

BACKGROUND: Recently we reported that activation of Epac1, an exchange protein activated by cAMP, increases melanoma cell migration via Ca (2+ )release from the endoplasmic reticulum (ER). G-protein βγ subunits (Gβγ) are known to act as an independent signaling molecule upon activation of G-protein...

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Detalles Bibliográficos
Autores principales:	Baljinnyam, Erdene, Umemura, Masanari, De Lorenzo, Mariana S, Xie, Lai-Hua, Nowycky, Martha, Iwatsubo, Mizuka, Chen, Suzie, Goydos, James S, Iwatsubo, Kousaku
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3141774/ https://www.ncbi.nlm.nih.gov/pubmed/21679469 http://dx.doi.org/10.1186/1471-2407-11-256

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