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Reduction in Reactive Oxygen Species Production by Mitochondria From Elderly Subjects With Normal and Impaired Glucose Tolerance
OBJECTIVE: Aging increases the risk of developing impaired glucose tolerance (IGT) and type 2 diabetes. It has been proposed that increased reactive oxygen species (ROS) generation by dysfunctional mitochondria could play a role in the pathogenesis of these metabolic abnormalities. We examined wheth...
Autores principales: | Ghosh, Sangeeta, Lertwattanarak, Raweewan, Lefort, Natalie, Molina-Carrion, Marjorie, Joya-Galeana, Joaquin, Bowen, Benjamin P., de Jesus Garduno-Garcia, Jose, Abdul-Ghani, Muhammad, Richardson, Arlan, DeFronzo, Ralph A., Mandarino, Lawrence, Van Remmen, Holly, Musi, Nicolas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142073/ https://www.ncbi.nlm.nih.gov/pubmed/21677280 http://dx.doi.org/10.2337/db11-0121 |
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