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A Low-Oxygenated Subpopulation of Pancreatic Islets Constitutes a Functional Reserve of Endocrine Cells

OBJECTIVE: The blood perfusion of pancreatic islets is highly variable and tightly regulated by the blood glucose concentration. Thus, oxygen levels are considered crucial for islet metabolism and function. Although islet oxygenation has been extensively studied in vitro, little is known about it in...

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Detalles Bibliográficos
Autores principales: Olsson, Richard, Carlsson, Per-Ola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142080/
https://www.ncbi.nlm.nih.gov/pubmed/21788581
http://dx.doi.org/10.2337/db09-0877