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Severity of Diabetes Governs Vascular Lipoprotein Lipase by Affecting Enzyme Dimerization and Disassembly

OBJECTIVE: In diabetes, when glucose consumption is restricted, the heart adapts to use fatty acid (FA) exclusively. The majority of FA provided to the heart comes from the breakdown of circulating triglyceride (TG), a process catalyzed by lipoprotein lipase (LPL) located at the vascular lumen. The...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Puthanveetil, Prasanth, Wang, Fang, Kim, Min Suk, Abrahani, Ashraf, Rodrigues, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142087/
https://www.ncbi.nlm.nih.gov/pubmed/21646389
http://dx.doi.org/10.2337/db11-0042