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Structural Analysis of Papain-Like NlpC/P60 Superfamily Enzymes with a Circularly Permuted Topology Reveals Potential Lipid Binding Sites
NlpC/P60 superfamily papain-like enzymes play important roles in all kingdoms of life. Two members of this superfamily, LRAT-like and YaeF/YiiX-like families, were predicted to contain a catalytic domain that is circularly permuted such that the catalytic cysteine is located near the C-terminus, ins...
Autores principales: | Xu, Qingping, Rawlings, Neil D., Chiu, Hsiu-Ju, Jaroszewski, Lukasz, Klock, Heath E., Knuth, Mark W., Miller, Mitchell D., Elsliger, Marc-Andre, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142127/ https://www.ncbi.nlm.nih.gov/pubmed/21799766 http://dx.doi.org/10.1371/journal.pone.0022013 |
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