Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909

BACKGROUND: Inhibition of parasite growth is a major objective of blood-stage malaria vaccines. The in vitro assay of parasite growth inhibitory activity (GIA) is widely used as a surrogate marker for malaria vaccine efficacy in the down-selection of candidate blood-stage vaccines. Here we report th...

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Detalles Bibliográficos
Autores principales: Duncan, Christopher J. A., Sheehy, Susanne H., Ewer, Katie J., Douglas, Alexander D., Collins, Katharine A., Halstead, Fenella D., Elias, Sean C., Lillie, Patrick J., Rausch, Kelly, Aebig, Joan, Miura, Kazutoyo, Edwards, Nick J., Poulton, Ian D., Hunt-Cooke, Angela, Porter, David W., Thompson, Fiona M., Rowland, Ros, Draper, Simon J., Gilbert, Sarah C., Fay, Michael P., Long, Carole A., Zhu, Daming, Wu, Yimin, Martin, Laura B., Anderson, Charles F., Lawrie, Alison M., Hill, Adrian V. S., Ellis, Ruth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142129/
https://www.ncbi.nlm.nih.gov/pubmed/21799809
http://dx.doi.org/10.1371/journal.pone.0022271

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