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Differential Inhibitory Effects of CysLT(1) Receptor Antagonists on P2Y(6) Receptor-Mediated Signaling and Ion Transport in Human Bronchial Epithelia

BACKGROUND: Cysteinyl leukotriene (CysLT) is one of the proinflammatory mediators released by the bronchi during inflammation. CysLTs exert their biological effects via specific G-protein-coupled receptors. CysLT(1) receptor antagonists are available for clinical use for the treatment of asthma. Rec...

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Detalles Bibliográficos
Autores principales:	Lau, Wendy Ka-hoi, Chow, Alison Wai-ming, Au, Simon Chak-leung, Ko, Wing-hung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142161/ https://www.ncbi.nlm.nih.gov/pubmed/21799837 http://dx.doi.org/10.1371/journal.pone.0022363

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