Cargando…
Differential Inhibitory Effects of CysLT(1) Receptor Antagonists on P2Y(6) Receptor-Mediated Signaling and Ion Transport in Human Bronchial Epithelia
BACKGROUND: Cysteinyl leukotriene (CysLT) is one of the proinflammatory mediators released by the bronchi during inflammation. CysLTs exert their biological effects via specific G-protein-coupled receptors. CysLT(1) receptor antagonists are available for clinical use for the treatment of asthma. Rec...
Autores principales: | Lau, Wendy Ka-hoi, Chow, Alison Wai-ming, Au, Simon Chak-leung, Ko, Wing-hung |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142161/ https://www.ncbi.nlm.nih.gov/pubmed/21799837 http://dx.doi.org/10.1371/journal.pone.0022363 |
Ejemplares similares
-
Expression of cysLT1 and cysLT2 Receptor in Chronic Hyperplastic Eosinophilic Sinusitis
por: Ouyang, Yuhui, et al.
Publicado: (2009) -
Cysteinyl leukotrienes regulate endothelial cell inflammatory and proliferative signals through CysLT(2) and CysLT(1) receptors
por: Duah, Ernest, et al.
Publicado: (2013) -
CysLT1 receptor antagonist alleviates pathogenesis of collagen-induced arthritis mouse model
por: Xu, Minwen, et al.
Publicado: (2017) -
Baicalin Ameliorates Radiation-Induced Lung Injury by Inhibiting the CysLTs/CysLT1 Signaling Pathway
por: Bao, Wu-An, et al.
Publicado: (2022) -
CysLT(1)R Antagonists Inhibit Tumor Growth in a Xenograft Model of Colon Cancer
por: Savari, Sayeh, et al.
Publicado: (2013)