Virus-like particle production with yeast: ultrastructural and immunocytochemical insights into Pichia pastoris producing high levels of the Hepatitis B surface antigen

BACKGROUND: A protective immune response against Hepatitis B infection can be obtained through the administration of a single viral polypeptide, the Hepatitis B surface antigen (HBsAg). Thus, the Hepatitis B vaccine is generated through the utilization of recombinant DNA technology, preferentially b...

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Detalles Bibliográficos
Autores principales: Lünsdorf, Heinrich, Gurramkonda, Chandrasekhar, Adnan, Ahmad, Khanna, Navin, Rinas, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142206/
https://www.ncbi.nlm.nih.gov/pubmed/21703024
http://dx.doi.org/10.1186/1475-2859-10-48

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