Vitamin A decreases pre-receptor amplification of glucocorticoids in obesity: study on the effect of vitamin A on 11beta-hydroxysteroid dehydrogenase type 1 activity in liver and visceral fat of WNIN/Ob obese rats

BACKGROUND: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) catalyzes the conversion of inactive glucocorticoids to active glucocorticoids and its inhibition ameliorates obesity and metabolic syndrome. So far, no studies have reported the effect of dietary vitamin A on 11β-HSD1 activity in viscer...

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Autores principales: Sakamuri, Vara Prasad SS, Ananthathmakula, Prashanth, Veettil, Giridharan Nappan, Ayyalasomayajula, Vajreswari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142207/
https://www.ncbi.nlm.nih.gov/pubmed/21696642
http://dx.doi.org/10.1186/1475-2891-10-70

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