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Chronic inhibition of endoplasmic reticulum calcium-release channels and calcium-ATPase lengthens the period of hepatic clock gene Per1

BACKGROUND: The role played by calcium as a regulator of circadian rhythms is not well understood. The effect of the pharmacological inhibition of the ryanodine receptor (RyR), inositol 1,4,5-trisphosphate receptor (IP(3)R), and endoplasmic-reticulum Ca(2+)-ATPase (SERCA), as well as the intracellul...

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Detalles Bibliográficos
Autores principales: Báez-Ruiz, Adrián, Díaz-Muñoz, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142245/
https://www.ncbi.nlm.nih.gov/pubmed/21740569
http://dx.doi.org/10.1186/1740-3391-9-6