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Chronic inhibition of endoplasmic reticulum calcium-release channels and calcium-ATPase lengthens the period of hepatic clock gene Per1
BACKGROUND: The role played by calcium as a regulator of circadian rhythms is not well understood. The effect of the pharmacological inhibition of the ryanodine receptor (RyR), inositol 1,4,5-trisphosphate receptor (IP(3)R), and endoplasmic-reticulum Ca(2+)-ATPase (SERCA), as well as the intracellul...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142245/ https://www.ncbi.nlm.nih.gov/pubmed/21740569 http://dx.doi.org/10.1186/1740-3391-9-6 |