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Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain

BACKGROUND: The exact mechanism of knee osteoarthritis (OA)-associated pain is unclear, whereas mixed evidence of inflammatory pain and neuropathic pain has been noted. We aimed to investigate pain-related sensory innervation in a monoiodoacetate (MIA)-induced model of OA. METHODS: Sixty of seventy...

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Detalles Bibliográficos
Autores principales: Orita, Sumihisa, Ishikawa, Tetsuhiro, Miyagi, Masayuki, Ochiai, Nobuyasu, Inoue, Gen, Eguchi, Yawara, Kamoda, Hiroto, Arai, Gen, Toyone, Tomoaki, Aoki, Yasuchika, Kubo, Takekazu, Takahashi, Kazuhisa, Ohtori, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142251/
https://www.ncbi.nlm.nih.gov/pubmed/21679434
http://dx.doi.org/10.1186/1471-2474-12-134

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