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Functional assays to determine the significance of two common XPC 3'UTR variants found in bladder cancer patients

BACKGROUND: XPC is involved in the nucleotide excision repair of DNA damaged by carcinogens known to cause bladder cancer. Individuals homozygous for the variant allele of XPC c.1496C > T (p.Ala499Val) were shown in a large pooled analysis to have an increased bladder cancer risk, and we found tw...

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Detalles Bibliográficos
Autores principales:	Qiao, Boling, Scott, Gina B, Elliott, Faye, Vaslin, Laurence, Bentley, Johanne, Hall, Janet, Bishop, D Timothy, Knowles, Margaret A, Kiltie, Anne E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142493/ https://www.ncbi.nlm.nih.gov/pubmed/21689419 http://dx.doi.org/10.1186/1471-2350-12-84

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