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Improving pan-genome annotation using whole genome multiple alignment

BACKGROUND: Rapid annotation and comparisons of genomes from multiple isolates (pan-genomes) is becoming commonplace due to advances in sequencing technology. Genome annotations can contain inconsistencies and errors that hinder comparative analysis even within a single species. Tools are needed to...

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Detalles Bibliográficos
Autores principales: Angiuoli, Samuel V, Dunning Hotopp, Julie C, Salzberg, Steven L, Tettelin, Hervé
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142524/
https://www.ncbi.nlm.nih.gov/pubmed/21718539
http://dx.doi.org/10.1186/1471-2105-12-272