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Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HT™ and Montanide ISA 51 in rhesus macaques

BACKGROUND: Increasing the breadth of the functional antibody response through immunization with Plasmodium falciparum apical membrane antigen 1 (PfAMA1) multi-allele vaccine formulations has been demonstrated in several rodent and rabbit studies. This study assesses the safety and immunogenicity of...

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Detalles Bibliográficos
Autores principales: Kusi, Kwadwo A, Remarque, Edmond J, Riasat, Vanessa, Walraven, Vanessa, Thomas, Alan W, Faber, Bart W, Kocken, Clemens HM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142537/
https://www.ncbi.nlm.nih.gov/pubmed/21726452
http://dx.doi.org/10.1186/1475-2875-10-182