The treatment of early breast cancer in women over the age of 70

One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarise...

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Detalles Bibliográficos
Autores principales: Ring, A, Reed, M, Leonard, R, Kunkler, I, Muss, H, Wildiers, H, Fallowfield, L, Jones, A, Coleman, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142812/
https://www.ncbi.nlm.nih.gov/pubmed/21694726
http://dx.doi.org/10.1038/bjc.2011.234
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author Ring, A
Reed, M
Leonard, R
Kunkler, I
Muss, H
Wildiers, H
Fallowfield, L
Jones, A
Coleman, R
author_facet Ring, A
Reed, M
Leonard, R
Kunkler, I
Muss, H
Wildiers, H
Fallowfield, L
Jones, A
Coleman, R
author_sort Ring, A
collection PubMed
description One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarises the existing evidence surrounding the management of early breast cancer in women aged 70 and over. The use of primary surgery and endocrine therapy, and adjuvant chemotherapy, radiotherapy, endocrine therapy and trastuzumab are discussed. Reference is made to ongoing clinical trials in this area and areas of controversy are highlighted.
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spelling pubmed-31428122012-07-12 The treatment of early breast cancer in women over the age of 70 Ring, A Reed, M Leonard, R Kunkler, I Muss, H Wildiers, H Fallowfield, L Jones, A Coleman, R Br J Cancer Minireview One third of all breast cancers are diagnosed in women aged 70 or over. Older women are a heterogeneous population who are under-represented in clinical trials, and as a result uncertainty can exist as to what represents optimal treatment. This minireview, from an international authorship, summarises the existing evidence surrounding the management of early breast cancer in women aged 70 and over. The use of primary surgery and endocrine therapy, and adjuvant chemotherapy, radiotherapy, endocrine therapy and trastuzumab are discussed. Reference is made to ongoing clinical trials in this area and areas of controversy are highlighted. Nature Publishing Group 2011-07-12 2011-06-21 /pmc/articles/PMC3142812/ /pubmed/21694726 http://dx.doi.org/10.1038/bjc.2011.234 Text en Copyright © 2011 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Ring, A
Reed, M
Leonard, R
Kunkler, I
Muss, H
Wildiers, H
Fallowfield, L
Jones, A
Coleman, R
The treatment of early breast cancer in women over the age of 70
title The treatment of early breast cancer in women over the age of 70
title_full The treatment of early breast cancer in women over the age of 70
title_fullStr The treatment of early breast cancer in women over the age of 70
title_full_unstemmed The treatment of early breast cancer in women over the age of 70
title_short The treatment of early breast cancer in women over the age of 70
title_sort treatment of early breast cancer in women over the age of 70
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142812/
https://www.ncbi.nlm.nih.gov/pubmed/21694726
http://dx.doi.org/10.1038/bjc.2011.234
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