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Intravesical therapy for urothelial carcinoma of the bladder

Transurethral resection is an effective therapy for non-muscle-invasive bladder cancer. However, the high rates of recurrence and significant risk of progression in higher grade tumors mandates additional therapy with intravesical agents. In this review we discuss the role of various intravesical ag...

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Detalles Bibliográficos
Autor principal: Manoharan, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142838/
https://www.ncbi.nlm.nih.gov/pubmed/21814318
http://dx.doi.org/10.4103/0970-1591.82846
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author Manoharan, M.
author_facet Manoharan, M.
author_sort Manoharan, M.
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description Transurethral resection is an effective therapy for non-muscle-invasive bladder cancer. However, the high rates of recurrence and significant risk of progression in higher grade tumors mandates additional therapy with intravesical agents. In this review we discuss the role of various intravesical agents currently in use including the immunomodualtory agent BCG and chemotherapeutic agents. We discuss the current guidelines and the role of these therapeutic agents in the context of higher grade Ta and T1 tumors.
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spelling pubmed-31428382011-08-03 Intravesical therapy for urothelial carcinoma of the bladder Manoharan, M. Indian J Urol Symposium Transurethral resection is an effective therapy for non-muscle-invasive bladder cancer. However, the high rates of recurrence and significant risk of progression in higher grade tumors mandates additional therapy with intravesical agents. In this review we discuss the role of various intravesical agents currently in use including the immunomodualtory agent BCG and chemotherapeutic agents. We discuss the current guidelines and the role of these therapeutic agents in the context of higher grade Ta and T1 tumors. Medknow Publications 2011 /pmc/articles/PMC3142838/ /pubmed/21814318 http://dx.doi.org/10.4103/0970-1591.82846 Text en © Indian Journal of Urology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Symposium
Manoharan, M.
Intravesical therapy for urothelial carcinoma of the bladder
title Intravesical therapy for urothelial carcinoma of the bladder
title_full Intravesical therapy for urothelial carcinoma of the bladder
title_fullStr Intravesical therapy for urothelial carcinoma of the bladder
title_full_unstemmed Intravesical therapy for urothelial carcinoma of the bladder
title_short Intravesical therapy for urothelial carcinoma of the bladder
title_sort intravesical therapy for urothelial carcinoma of the bladder
topic Symposium
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142838/
https://www.ncbi.nlm.nih.gov/pubmed/21814318
http://dx.doi.org/10.4103/0970-1591.82846
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