MicroRNA Involved in Inflammation: Control of Eicosanoid Pathway

MicroRNAs (miRNAs) have emerged as important regulators in human physiological and pathological processes. Recent investigations implicated the involvement of miRNAs in the immune system development and function and demonstrated an unexpected new regulatory level. We summarize the current knowledge...

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Detalles Bibliográficos
Autores principales: Ochs, Meike J., Steinhilber, Dieter, Suess, Beatrix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142860/
https://www.ncbi.nlm.nih.gov/pubmed/21811464
http://dx.doi.org/10.3389/fphar.2011.00039
Descripción
Sumario:MicroRNAs (miRNAs) have emerged as important regulators in human physiological and pathological processes. Recent investigations implicated the involvement of miRNAs in the immune system development and function and demonstrated an unexpected new regulatory level. We summarize the current knowledge about miRNA control in the development of the immune system and discuss their role in the immune and inflammatory responses with a special focus on eicosanoid signaling.

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