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Antisense-Mediated RNA Targeting: Versatile and Expedient Genetic Manipulation in the Brain
A limiting factor in brain research still is the difficulty to evaluate in vivo the role of the increasing number of proteins implicated in neuronal processes. We discuss here the potential of antisense-mediated RNA targeting approaches. We mainly focus on those that manipulate splicing (exon skippi...
Autores principales: | Zalachoras, Ioannis, Evers, Melvin M., van Roon-Mom, Willeke M. C., Aartsma-Rus, Annemieke M., Meijer, Onno C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142880/ https://www.ncbi.nlm.nih.gov/pubmed/21811437 http://dx.doi.org/10.3389/fnmol.2011.00010 |
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