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Sodium arsenite and hyperthermia modulate cisplatin-DNA damage responses and enhance platinum accumulation in murine metastatic ovarian cancer xenograft after hyperthermic intraperitoneal chemotherapy (HIPEC)

BACKGROUND: Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer death in the USA. Recurrence rates are high after front-line therapy and most patients eventually die from platinum (Pt) - resistant disease. Cisplatin resistance is associated with increased nucleotide excision r...

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Detalles Bibliográficos
Autores principales:	Muenyi, Clarisse S, States, Vanessa A, Masters, Joshua H, Fan, Teresa W, Helm, C William, States, J Christopher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143084/ https://www.ncbi.nlm.nih.gov/pubmed/21696631 http://dx.doi.org/10.1186/1757-2215-4-9

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