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Real time analysis of β(2)-adrenoceptor-mediated signaling kinetics in Human Primary Airway Smooth Muscle Cells reveals both ligand and dose dependent differences
BACKGROUND: β(2)-adrenoceptor agonists elicit bronchodilator responses by binding to β(2)-adrenoceptors on airway smooth muscle (ASM). In vivo, the time between drug administration and clinically relevant bronchodilation varies significantly depending on the agonist used. Our aim was to utilise a fl...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143098/ https://www.ncbi.nlm.nih.gov/pubmed/21722392 http://dx.doi.org/10.1186/1465-9921-12-89 |