Real time analysis of β(2)-adrenoceptor-mediated signaling kinetics in Human Primary Airway Smooth Muscle Cells reveals both ligand and dose dependent differences

BACKGROUND: β(2)-adrenoceptor agonists elicit bronchodilator responses by binding to β(2)-adrenoceptors on airway smooth muscle (ASM). In vivo, the time between drug administration and clinically relevant bronchodilation varies significantly depending on the agonist used. Our aim was to utilise a fl...

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Detalles Bibliográficos
Autores principales: Billington, Charlotte K, Hall, Ian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143098/
https://www.ncbi.nlm.nih.gov/pubmed/21722392
http://dx.doi.org/10.1186/1465-9921-12-89

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