Microneedle Array Design Determines the Induction of Protective Memory CD8(+) T Cell Responses Induced by a Recombinant Live Malaria Vaccine in Mice

BACKGROUND: Vaccine delivery into the skin has received renewed interest due to ease of access to the immune system and microvasculature, however the stratum corneum (SC), must be breached for successful vaccination. This has been achieved by removing the SC by abrasion or scarification or by delive...

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Detalles Bibliográficos
Autores principales: Carey, John B., Pearson, Frances E., Vrdoljak, Anto, McGrath, Marie G., Crean, Abina M., Walsh, Patrick T., Doody, Timothy, O'Mahony, Conor, Hill, Adrian V. S., Moore, Anne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143140/
https://www.ncbi.nlm.nih.gov/pubmed/21799855
http://dx.doi.org/10.1371/journal.pone.0022442

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