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ChIP-seq Defined Genome-Wide Map of TGFβ/SMAD4 Targets: Implications with Clinical Outcome of Ovarian Cancer

Deregulation of the transforming growth factor-β (TGFβ) signaling pathway in epithelial ovarian cancer has been reported, but the precise mechanism underlying disrupted TGFβ signaling in the disease remains unclear. We performed chromatin immunoprecipitation followed by sequencing (ChIP-seq) to inve...

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Detalles Bibliográficos
Autores principales: Kennedy, Brian A., Deatherage, Daniel E., Gu, Fei, Tang, Binhua, Chan, Michael W. Y., Nephew, Kenneth P., Huang, Tim H-M., Jin, Victor X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143154/
https://www.ncbi.nlm.nih.gov/pubmed/21799915
http://dx.doi.org/10.1371/journal.pone.0022606

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