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Regulation of C3a Receptor Signaling in Human Mast Cells by G Protein Coupled Receptor Kinases

BACKGROUND: The complement component C3a activates human mast cells via its cell surface G protein coupled receptor (GPCR) C3aR. For most GPCRs, agonist-induced receptor phosphorylation leads to receptor desensitization, internalization as well as activation of downstream signaling pathways such as...

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Detalles Bibliográficos
Autores principales:	Guo, Qiang, Subramanian, Hariharan, Gupta, Kshitij, Ali, Hydar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143157/ https://www.ncbi.nlm.nih.gov/pubmed/21799898 http://dx.doi.org/10.1371/journal.pone.0022559

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