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Performance of Ultra-Deep Pyrosequencing in Analysis of HIV-1 pol Gene Variation
INTRODUCTION: Ultra-deep pyrosequencing (UDPS) has been used to detect minority variants within HIV-1 populations. Some aspects of the quality and reproducibility of UDPS have been previously evaluated, but comprehensive studies are still needed. PRINCIPAL FINDING: In this study the UDPS technology...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143174/ https://www.ncbi.nlm.nih.gov/pubmed/21799940 http://dx.doi.org/10.1371/journal.pone.0022741 |