Liver-Derived IGF-I Regulates Mean Life Span in Mice

BACKGROUND: Transgenic mice with low levels of global insulin-like growth factor-I (IGF-I) throughout their life span, including pre- and postnatal development, have increased longevity. This study investigated whether specific deficiency of liver-derived, endocrine IGF-I is of importance for life s...

Descripción completa

Detalles Bibliográficos
Autores principales: Svensson, Johan, Sjögren, Klara, Fäldt, Jenny, Andersson, Niklas, Isaksson, Olle, Jansson, John-Olov, Ohlsson, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143189/
https://www.ncbi.nlm.nih.gov/pubmed/21799924
http://dx.doi.org/10.1371/journal.pone.0022640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143189/
https://www.ncbi.nlm.nih.gov/pubmed/21799924
http://dx.doi.org/10.1371/journal.pone.0022640

Ejemplares similares