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Mechanism and Substrate Recognition of 2-Hydroxyethylphosphonate Dioxygenase

[Image: see text] HEPD belongs to the superfamily of 2-His-1-carboxylate non-heme iron-dependent dioxygenases. It converts 2-hydroxyethylphosphonate (2-HEP) to hydroxymethylphosphonate (HMP) and formate. Previously postulated mechanisms for the reaction catalyzed by HEPD cannot explain its conversio...

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Detalles Bibliográficos
Autores principales:	Peck, Spencer C., Cooke, Heather A., Cicchillo, Robert M., Malova, Petra, Hammerschmidt, Friedrich, Nair, Satish K., van der Donk, Wilfred A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2011
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143709/ https://www.ncbi.nlm.nih.gov/pubmed/21711001 http://dx.doi.org/10.1021/bi200804r

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